BOC Blood Bank Practice Exam 2026 – Complete Preparation Guide

In an emergency scenario where Rh-negative red cells are transfused into an Rh-positive person with the genotype CDe/CDe, the most likely antibody to develop is anti-c. This is because the recipient’s genotype indicates they have the CDe haplotype, which means they express the D antigen and also possess the c and e antigens.

When Rh-negative red cells, which lack the D antigen, are transfused, the Rh-positive individual, who already has the c and e antigens, is likely to produce an antibody against the c antigen if the transfused Rh-negative red cells come from a donor who possesses the C antigen. This is particularly relevant because sensitization to the c antigen can occur if the individual is exposed to it, leading to the formation of anti-c antibodies.

The options that mention the D, e, and E antigens are not as relevant here. Since the patient is already Rh-positive (D antigen positive), the development of anti-D antibodies is unlikely unless the patient were to be further sensitized or if they were to have an immune response due to other reasons. The involvement of the e and E antigens is also less significant compared to the c antigen in the context of this case. Therefore, the likelihood of