BOC Blood Bank Practice Exam 2026 – Complete Preparation Guide

When evaluating the reaction of a patient's red blood cells with specific antisera, it is important to understand the significance of the blood group antigens being tested. In this case, a positive reaction with anti-D antisera indicates that the patient's red blood cells possess the D antigen, making them Rh positive. The D antigen is one of the key components in the Rh blood group system, which is crucial for determining a patient's Rh type.

In contrast, a positive reaction with anti-A would reveal the presence of A antigens, while a reaction with anti-B would indicate B antigens, both of which are unrelated to the Rh group. The anti-E antisera checks for the presence of another antigen within the Rh system, but a positive result with anti-D is specifically required to classify the blood as Rh positive. Therefore, the presence of D antigens on the red blood cells confirms the classification and significance of this positive reaction, particularly in transfusion medicine and pregnancy management, where Rh compatibility is essential.